Α-Cyclodextrin

Α-Cyclodextrin
Names
	IUPAC name cyclomaltohexaose
	Systematic IUPAC name cyclohexakis-(1→4)-α-D-glucopyranosyl
	Other names Cyclohexaamylose; Cyclohexadextrin; Cyclomaltohexose; α-Cycloamylose; α-Dextrin
Identifiers
CAS Number	10016-20-3 (hydrate) ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:40585;
ChEMBL	ChEMBL1230813;
ChemSpider	392705;
DrugBank	DB01909;
ECHA InfoCard	100.029.995
EC Number	233-007-4;
KEGG	D08846;
PubChem CID	444913;
UNII	Z1LH97KTRM (hydrate) ;
CompTox Dashboard (EPA)	DTXSID7030698 ;
	InChI InChI=1S/C36H60O30/c37-1-7-25-13(43)19(49)31(55-7)62-26-8(2-38)57-33(21(51)15(26)45)64-28-10(4-40)59-35(23(53)17(28)47)66-30-12(6-42)60-36(24(54)18(30)48)65-29-11(5-41)58-34(22(52)16(29)46)63-27-9(3-39)56-32(61-25)20(50)14(27)44/h7-54H,1-6H2/t7-,8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-/m1/s1 Key: HFHDHCJBZVLPGP-RWMJIURBSA-N;
	SMILES C([C@@H]1[C@@H]2[C@@H]([C@H]([C@H](O1)O[C@@H]3[C@H](O[C@@H]([C@@H]([C@H]3O)O)O[C@@H]4[C@H](O[C@@H]([C@@H]([C@H]4O)O)O[C@@H]5[C@H](O[C@@H]([C@@H]([C@H]5O)O)O[C@@H]6[C@H](O[C@@H]([C@@H]([C@H]6O)O)O[C@@H]7[C@H](O[C@H](O2)[C@@H]([C@H]7O)O)CO)CO)CO)CO)CO)O)O)O;
Properties
Chemical formula	C36H60O30
Molar mass	972.846 g·mol−1
Appearance	white solid
Melting point	507 °C (945 °F; 780 K) at fast heating rates, decomposition below 300 °C for conventional heating
Solubility in water	14.5 g/100 mL
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

α-Cyclodextrin (alpha-cyclodextrin), sometimes abbreviated as α-CD, is a hexasaccharide derived from glucose. It is related to the β- (beta) and γ- (gamma) cyclodextrins, which contain seven and eight glucose units, respectively. All cyclodextrins are white, water-soluble solids with minimal toxicity. Cyclodextrins tend to bind other molecules in their quasi-cylindrical, lipophilic interiors. The compound is of wide interest because it exhibits host–guest properties, forming inclusion compounds. This inclusion (and release) behavior leads to applications in medicine.

Names

IUPAC name cyclomaltohexaose
Systematic IUPAC name cyclohexakis-(1→4)-α-D-glucopyranosyl
Other names Cyclohexaamylose Cyclohexadextrin Cyclomaltohexose α-Cycloamylose α-Dextrin
Identifiers
CAS Number	10016-20-3 (hydrate)^Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:40585
ChEMBL	ChEMBL1230813
ChemSpider	392705
DrugBank	DB01909
ECHA InfoCard	100.029.995
EC Number	233-007-4
KEGG	D08846
PubChem CID	444913
UNII	Z1LH97KTRM (hydrate)^Y
CompTox Dashboard (EPA)	DTXSID7030698
InChI InChI=1S/C36H60O30/c37-1-7-25-13(43)19(49)31(55-7)62-26-8(2-38)57-33(21(51)15(26)45)64-28-10(4-40)59-35(23(53)17(28)47)66-30-12(6-42)60-36(24(54)18(30)48)65-29-11(5-41)58-34(22(52)16(29)46)63-27-9(3-39)56-32(61-25)20(50)14(27)44/h7-54H,1-6H2/t7-,8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-/m1/s1 Key: HFHDHCJBZVLPGP-RWMJIURBSA-N
SMILES C([C@@H]1[C@@H]2[C@@H]([C@H]([C@H](O1)O[C@@H]3[C@H](O[C@@H]([C@@H]([C@H]3O)O)O[C@@H]4[C@H](O[C@@H]([C@@H]([C@H]4O)O)O[C@@H]5[C@H](O[C@@H]([C@@H]([C@H]5O)O)O[C@@H]6[C@H](O[C@@H]([C@@H]([C@H]6O)O)O[C@@H]7[C@H](O[C@H](O2)[C@@H]([C@H]7O)O)CO)CO)CO)CO)CO)O)O)O
Properties
Chemical formula	C₃₆H₆₀O₃₀
Molar mass	972.846 g·mol⁻¹
Appearance	white solid
Melting point	507 °C (945 °F; 780 K) at fast heating rates, decomposition below 300 °C for conventional heating
Solubility in water	14.5 g/100 mL
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references