Δ-3-Tetrahydrocannabinol

Δ³-Tetrahydrocannabinol (often abbreviated as delta-3-THC or Δ³-THC) is a synthetic isomer of tetrahydrocannabinol (THC) developed during the original research in the 1940s to develop synthetic routes to the natural products Δ⁸-THC and Δ⁹-THC found in the cannabis. While the normal trans configuration of THC is in this case flattened by the double bond, it still has two enantiomers as the 9-methyl group can exist in an (R) or (S) conformation. The (S) enantiomer has similar effects to Δ⁹-THC though with several times lower potency, while the (R) enantiomer is many times less active or inactive, depending on the assay used. It has been identified as a component of vaping liquid products.