(R)-1-Aminoindane

(R)-1-Aminoindane
Clinical data
Other names	(R)-1-Aminoindan; (R)-(–)-1-Aminoindan; (R)-AI; (R)-1-AI; TVP-136; TV-136; (R)-(−)-1-Indanamine
Identifiers
	IUPAC name (1R)-2,3-dihydro-1H-inden-1-amine;
CAS Number	10277-74-4;
PubChem CID	2733933;
ChemSpider	2015696;
UNII	I17RC77CJ2;
ChEMBL	ChEMBL4573666;
Chemical and physical data
Formula	C9H11N
Molar mass	133.194 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C1CC2=CC=CC=C2[C@@H]1N;
	InChI InChI=1S/C9H11N/c10-9-6-5-7-3-1-2-4-8(7)9/h1-4,9H,5-6,10H2/t9-/m1/s1; Key:XJEVHMGJSYVQBQ-SECBINFHSA-N;

(R)-1-Aminoindane ((R)-1-AI; developmental code name TVP-136 or TV-136), or (R)-1-aminoindan, is the major metabolite of the selective MAO-B inhibitor and antiparkinsonian agent rasagiline ((R)-N-propargyl-1-aminoindane). In contrast to rasagiline, it lacks significant monoamine oxidase inhibition. In addition, unlike selegiline and its amphetamine metabolites, it lacks monoamine reuptake-inhibiting and -releasing activities and associated amphetamine-like psychostimulant effects. However, (R)-1-aminoindane retains neuroprotective effects and certain other activities.