1,1,3,3-Tetramethylguanidine

1,1,3,3-Tetramethylguanidine
Names
	Preferred IUPAC name N,N,N′,N′-Tetramethylguanidine
Identifiers
CAS Number	80-70-6 ;
3D model (JSmol)	Interactive image;
Beilstein Reference	969608
ChemSpider	59832 ;
ECHA InfoCard	100.001.185
EC Number	201-302-7;
MeSH	1,1,3,3-tetramethylguanidine
PubChem CID	66460;
UNII	VEZ101E7ZU ;
UN number	2920
CompTox Dashboard (EPA)	DTXSID2058835 ;
	InChI InChI=1S/C5H13N3/c1-7(2)5(6)8(3)4/h6H,1-4H3 Key: KYVBNYUBXIEUFW-UHFFFAOYSA-N ;
	SMILES CN(C)C(=N)N(C)C;
Properties
Chemical formula	C5H13N3
Molar mass	115.180 g·mol−1
Appearance	Colourless liquid
Density	918 mg mL−1
Melting point	−30 °C (−22 °F; 243 K)
Boiling point	160 to 162 °C (320 to 324 °F; 433 to 435 K)
Solubility in water	Miscible
Vapor pressure	30 Pa (at 20 °C)
Acidity (pKa)	13.0±1.0 (pKa of conjugate acid in water)
Refractive index (nD)	1.469
Hazards
	GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H226, H302, H314
Precautionary statements	P280, P305+P351+P338, P310
Flash point	60 °C (140 °F; 333 K)
Explosive limits	1–7.5%
Related compounds
Related compounds	Tetramethylurea; Noxytiolin; Metformin; Buformin; Allantoic acid; Carmustine;
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Tetramethylguanidine is an organic compound with the formula HNC(N(CH₃)₂)₂. This colourless liquid is a strong base, as judged by the high pK_a of its' conjugate acid.

It was originally prepared from tetramethylthiourea via S-methylation and amination, but alternative methods start from cyanogen iodide.