1,2-Diarylethylamine

1,2-Diarylethylamine
Drug class
1,2-Diphenylethylamine, the parent structure of most of the 1,2-diarylethylamines
Class identifiers
Synonyms1,2-Diphenylethylamines
UseResearch chemicals;
some as designer drugs
Mode of actionDissociative
Mechanism of actionAntagonist
Biological targetNMDA receptor
Chemical classArylalkylamine
Legal status

1,2-Diarylethylamines are a class of psychoactive compounds defined by two aryl groups attached to adjacent carbon atoms on an ethylamine backbone. These compounds display a range of pharmacological activities, most notably as NMDA receptor antagonists, and have attracted attention as dissociative designer drugs that produce feelings of detachment from reality or oneself.