1,5-Anhydroglucitol

1,5-Anhydroglucitol
Names
IUPAC name
1,5-Anhydro-D-glucitol
Systematic IUPAC name
(2R,3S,4R,5S)-2-(Hydroxymethyl)oxane-3,4,5-triol
Other names
  • 1-Deoxy-D-glucopyranose
  • 1,5-AG
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.005.301
EC Number
  • 205-829-3
UNII
  • InChI=1S/C6H12O5/c7-1-4-6(10)5(9)3(8)2-11-4/h3-10H,1-2H2/t3-,4+,5+,6+/m0/s1
    Key: MPCAJMNYNOGXPB-SLPGGIOYSA-N
  • C1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O
Properties
C6H12O5
Molar mass 164.157 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

1,5-Anhydroglucitol, also known as 1,5-AG, is a naturally occurring monosaccharide found in nearly all foods. Blood concentrations of 1,5-anhydroglucitol decrease during times of hyperglycemia above 180 mg/dL, and return to normal levels after approximately 2 weeks in the absence of hyperglycemia. As a result, it can be used for people with either type-1 or type-2 diabetes mellitus to identify glycemic variability or a history of high blood glucose even if current glycemic measurements such as hemoglobin A1c (HbA1c) and blood glucose monitoring have near normal values. Despite this possible use and its approval by the FDA, 1,5-AG tests are rarely ordered. There is some data suggesting that 1,5-AG values are useful to fill the gap and offer complementary information to HbA1c and fructosamine tests.

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