11β-Hydroxyprogesterone

11β-Hydroxyprogesterone
Names
	IUPAC name 11β-Hydroxypregn-4-ene-3,20-dione
	Systematic IUPAC name (1S,3aS,3bS,9aR,9bS,10S,11aS)-1-Acetyl-10-hydroxy-9a,11a-dimethyl-1,2,3,3a,3b,4,5,8,9,9a,9b,10,11,11a-tetradecahydro-7H-cyclopenta[a]phenanthren-7-one
	Other names 11β-OHP; 21-Deoxycorticosterone; 21-Desoxycorticosterone
Identifiers
CAS Number	600-57-7;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:28247;
ChEMBL	ChEMBL2440888;
ChemSpider	91968;
ECHA InfoCard	100.009.088
KEGG	C05498;
PubChem CID	101788;
CompTox Dashboard (EPA)	DTXSID701044492 ;
	InChI InChI=1S/C21H30O3/c1-12(22)16-6-7-17-15-5-4-13-10-14(23)8-9-20(13,2)19(15)18(24)11-21(16,17)3/h10,15-19,24H,4-9,11H2,1-3H3/t15-,16+,17-,18-,19+,20-,21+/m0/s1 Key: BFZHCUBIASXHPK-ATWVFEABSA-N;
	SMILES CC(=O)[C@H]1CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)O)C;
Properties
Chemical formula	C21H30O3
Molar mass	330.468 g/mol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

11β-Hydroxyprogesterone (11β-OHP), also known as 21-deoxycorticosterone, as well as 11β-hydroxypregn-4-ene-3,20-dione, is a naturally occurring, endogenous steroid and derivative of progesterone. It is a potent mineralocorticoid. Syntheses of 11β-OHP from progesterone is catalyzed by the steroid 11β-hydroxylase (CYP11B1) enzyme, and, to a lesser extent, by the aldosterone synthase enzyme (CYP11B2).