1751 Port-au-Prince earthquake
| Local date | November 21, 1751 |
|---|---|
| Magnitude | 8.0 Ms |
| Epicenter | 18°30′N 72°18′W / 18.5°N 72.3°W |
| Areas affected | Saint-Domingue |
| Casualties | unknown |
The 1751 Port-au-Prince earthquake occurred at 12:50 UTC on 21 November in Saint-Domingue, followed by a tsunami. Another earthquake was reported at the same location on 15 September of the same year and it is uncertain whether the two reports refer to the same event.