1888 U.S. National Championships – Men's singles

Men's singles
1888 U.S. National Championships
Champion Henry Slocum
Runner-up Richard Sears
Scorew/o

Henry Slocum defeated Howard Taylor in the all comers' final, 6–4, 6–1, 6–0 to win the men's singles tennis title at the 1888 U.S. National Championships. Slocum won the Challenge Round automatically, as the seven-time defending champion Richard Sears had retired earlier that year. The event was held at the Newport Casino, R.I.