1906 U.S. National Championships – Men's singles

Men's singles
1906 U.S. National Championships
Champion William Clothier
Runner-up Beals Wright
Score6–3, 6–0, 6–4

William Clothier defeated defending champion Beals Wright in the Challenge Round 6–3, 6–0, 6–4 to win the men's singles tennis title at the 1906 U.S. National Championships. Clothier had defeated Karl Behr in the All Comers' Final.

The event was held at the Newport Casino in Newport, R.I. in the United States.