1922 U.S. National Championships – Men's singles

Men's singles
1922 U.S. National Championships
Champion Bill Tilden
Runner-up Bill Johnston
Score4–6, 3–6, 6–2, 6–3, 6–4
Draw124
SeedsN.A.

Two-time defending champion Bill Tilden defeated Bill Johnston in the final, 4–6, 3–6, 6–2, 6–3, 6–4 to win the men's singles tennis title at the 1922 U.S. National Championships. It was Tilden's third U.S. Championships singles title and fifth major singles title overall.