1925 U.S. National Championships – Men's singles

Men's singles
1925 U.S. National Championships
Champion Bill Tilden
Runner-up Bill Johnston
Score4–6, 11–9, 6–3, 4–6, 6–3
Draw64
SeedsN.A.

Five-time defending champion Bill Tilden defeated Bill Johnston in the final, 4–6, 11–9, 6–3, 4–6, 6–3 to win the men's singles tennis title at the 1925 U.S. National Championships. It was Tilden's sixth U.S. Championships title and his eight major title overall.