1927 U.S. National Championships – Men's singles

Men's singles
1927 U.S. National Championships
Champion René Lacoste
Runner-up Bill Tilden
Score11–9, 6–3, 11–9
Draw64
Seeds16

Defending champion René Lacoste defeated Bill Tilden in the final, 11–9, 6–3, 11–9 to win the men's singles tennis title at the 1927 U.S. National Championships. It was Lacoste's second U.S. Championships singles title and fifth major singles title overall.