1942–43 League of Ireland
| Season | 1942–43 | 
|---|---|
| Champions | Cork United (3rd title) | 
| Matches played | 90 | 
| Goals scored | 339 (3.77 per match) | 
| Top goalscorer | Seán McCarthy (16 goals) | 
| Biggest home win | Limerick 7–0 Bray Unknowns | 
| Biggest away win | Bohemians 0–5 Shelbourne  Bray Unknowns 0–5 St James's Gate Bray Unknowns 0–5 Dundalk  | 
| Highest scoring | Bray Unknowns 5–4 Brideville | 
← 1941–42  1943–44 →   | |
The 1942–43 League of Ireland was the 22nd season of senior football in the Republic of Ireland. Cork United were the defending champions.