1944 U.S. National Championships – Women's singles

Women's singles
1944 U.S. National Championships
Champion Pauline Betz
Runner-up Margaret Osborne
Score6–3, 8–6
Draw32
Seeds8

First-seeded and reigning champion Pauline Betz defeated second-seeded Margaret Osborne 6–3, 8–6 in the final to win the women's singles tennis title at the 1944 U.S. National Championships. The tournament was played on outdoor grass courts and held from August 30 through September 4, 1944 at the West Side Tennis Club in Forest Hills, Queens, New York.

The draw consisted of 32 players of which eight were seeded.