1945 U.S. National Championships – Men's singles
| Men's singles | |
|---|---|
| 1945 U.S. National Championships | |
| Champion | Frank Parker |
| Runner-up | Bill Talbert |
| Score | 14–12, 6–1, 6–2 |
Frank Parker defeated Bill Talbert 14–12, 6–1, 6–2 in the final to win the men's singles tennis title at the 1945 U.S. National Championships.