1948 U.S. National Championships – Women's singles
| Women's singles | |
|---|---|
| 1948 U.S. National Championships | |
| Champion | Margaret Osborne duPont |
| Runner-up | Louise Brough |
| Score | 4–6, 6–4, 15–13 |
Third-seeded Margaret Osborne duPont defeated Louise Brough 4–6, 6–4, 15–13 in the final to win the women's singles tennis title at the 1948 U.S. National Championships.