1949 U.S. National Championships – Women's singles
| Women's singles | |
|---|---|
| 1949 U.S. National Championships | |
| Champion | Margaret Osborne duPont |
| Runner-up | Doris Hart |
| Score | 6–4, 6–1 |
Second-seeded Margaret Osborne duPont defeated Doris Hart 6–4, 6–1 in the final to win the women's singles tennis title at the 1949 U.S. National Championships.