1959 Giro d'Italia|
| Dates | 16 May - 7 June 1959 |
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| Stages | 22 |
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| Distance | 3,657 km (2,272 mi) |
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| Winning time | 101h 50' 26" |
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The 1959 Giro d'Italia was the 42nd running of the Giro d'Italia, one of cycling's Grand Tour races. The Giro started in Milan, on 16 May, with a 135 km (83.9 mi) stage and concluded back in Milan, on 7 June, with a 220 km (136.7 mi) leg. A total of 120 riders from 15 teams entered the 20-stage race, which was won by Luxembourgian Charly Gaul of the EMI team. The second and third places were taken by Frenchman Jacques Anquetil and Italian Diego Ronchini, respectively.