1965 Campeonato Profesional
| Season | 1965 |
|---|---|
| Champions | Deportivo Cali (1st title) |
| Matches played | 312 |
| Goals scored | 992 (3.18 per match) |
| Top goalscorer | Perfecto Rodríguez (38 goals) |
| Biggest home win | América de Cali 6–0 Cúcuta Deportivo Deportivo Cali 6–0 Deportes Quindío |
| Biggest away win | Independiente Medellín 1–5 Millonarios Cúcuta Deportivo 1–5 Santa Fe |
| Highest scoring | Millonarios 7–4 Independiente Medellín |
← 1964 1966 → | |
The 1965 Campeonato Profesional was the 18th season of Colombia's top-flight football league. 13 teams competed against one another. Deportivo Cali won their first league title in history, cutting a streak of four straight championships won by Millonarios.