1980–81 Challenge Cup

1980–81 Three Fives Challenge Cup
Duration5 Rounds
Number of teams32
Winners Widnes
Runners-up Hull Kingston Rovers
Lance Todd Trophy Mick Burke

The 1980–81 Challenge Cup was the 80th staging of rugby league's oldest knockout competition, the Challenge Cup. Known as the Three Fives Challenge Cup for sponsorship reasons, the final was contested by Widnes and Hull Kingston Rovers at Wembley, with Widnes winning 18–9.