1981 Primera División de Chile
| Dates | 11 July 1981 – 24 January 1982 |
|---|---|
| Champions | Colo-Colo (13th title) |
| Relegated | Ñublense Everton Deportes Concepción San Luis |
| 1982 Copa Libertadores | Colo-Colo Cobreloa (Liguilla winners) |
| Matches played | 240 |
| Goals scored | 661 (2.75 per match) |
| Top goalscorer | Carlos Caszely Luis Marcoleta Víctor Cabrera (20 goals) |
| Biggest home win | Naval 8–1 Ñublense (2 January 1982) |
| Highest attendance | 74,570 Universidad de Chile 0–2 Colo-Colo (13 December) |
| Total attendance | 1,991,278 |
| Average attendance | 8,567 |
← 1980 1982 → | |
The 1981 Campeonato Nacional was Chilean league top tier's 49th season. Colo-Colo was the tournament's champion, winning its thirteenth title.