1991 French Open – Women's singles

Defending champion Monica Seles defeated Arantxa Sánchez Vicario in the final, 6–3, 6–4 to win the women's singles title at the 1991 French Open. It was her second French Open title and third major title overall.

This tournament marked the most decisive defeat suffered by Steffi Graf at a major: she won just two games in the semifinals against Sánchez Vicario (a rematch of the 1989 final). It was also the first time since the 1987 Wimbledon Championships that Graf was not the top seed at a major.