1999–2000 Cypriot First Division
| Season | 1999–2000 |
|---|---|
| Champions | Anorthosis (11th title) |
| Relegated | Ethnikos Assia Anagennisi Alki |
| Champions League | Anorthosis (2nd qualifying round) |
| UEFA Cup | Omonia (qualifying round) APOEL (qualifying round; via Cypriot Cup) |
| Intertoto Cup | Nea Salamis (1st round) |
| Matches played | 182 |
| Goals scored | 670 (3.68 per match) |
| Top goalscorer | Rainer Rauffmann (34 goals) |
← 1998–99 2000–01 → | |
The 1999–2000 Cypriot First Division was the 61st season of the Cypriot top-level football league. Anorthosis won their 11th title.