1999–2000 Maltese Premier League
| Season | 1999–2000 | 
|---|---|
| Dates | 24 August 1999 – 29 April 2000 | 
| Champions | Birkirkara (1st title)  | 
| Relegated | Gozo Żurrieq  | 
| Champions League | Birkirkara | 
| UEFA Cup | Sliema Wanderers Valletta  | 
| UEFA Intertoto Cup | Floriana | 
| Matches played | 132 | 
| Goals scored | 462 (3.5 per match) | 
| Top goalscorer | Michael Mifsud (21 goals) | 
← 1998–99  2000–01 →   | |
The 1999–2000 Maltese Premier League (known as the Rothmans Premier League for sponsorship reasons) was the 20th season of the Maltese Premier League, and the 85th season of top-tier football in Malta. It was contested by 10 teams, and Birkirkara F.C. won the championship.