1999–2000 National Professional Soccer League season
| Season | 1999–2000 |
|---|---|
| Champions | Milwaukee Wave (2nd title) |
| Matches played | 264 |
| Top goalscorer | Hector Marinaro (103) |
| Average attendance | 5,430 |
← 1998–99 2000–01 → | |
The 1999–2000 National Professional Soccer League season was the sixteenth season for the league.