2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase

2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase
Identifiers
EC no.2.2.1.10
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins

2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase (EC 2.2.1.10, ADH synthase, ADHS, MJ0400 (gene)) is an enzyme with systematic name L-aspartate 4-semialdehyde:1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate methylglyoxaltransferase. This enzyme catalyses the following chemical reaction

L-aspartate 4-semialdehyde + 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + 2,3-dioxopropyl phosphate

The enzyme plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate.