2-hydroxyphytanoyl-CoA lyase

2-hydroxyacyl-CoA lyase 1
Identifiers
SymbolHACL1
Alt. symbolsHPCL
NCBI gene26061
HGNC17856
OMIM604300
RefSeqNM_012260
UniProtQ9UJ83
Other data
LocusChr. 3 p24.3
Search for
StructuresSwiss-model
DomainsInterPro

2-Hydroxyphytanoyl-CoA lyase is a peroxisomal enzyme involved in the catabolism of phytanoic acid by α-oxidation. It requires thiamine diphosphate (ThDP) as cofactor.

It is classified under EC number 4.1.