2001 Indian Wells Open – Women's singles

Women's singles
2001 Indian Wells Open
Champion Serena Williams
Runner-up Kim Clijsters
Score4–6, 6–4, 6–2
Draw96
Seeds32

Serena Williams defeated Kim Clijsters in the final, 4–6, 6–4, 6–2 to win the women's singles tennis title at the 2001 Indian Wells Open. This would be the final time Williams would attend the Indian Wells Open until 2015, due to a boycott of the tournament by both Williams sisters in protest of alleged racist remarks by crowd members. Venus Williams would not return to the tournament until 2016.

Lindsay Davenport was the defending champion, but lost in the quarterfinals to Serena Williams.