2005–06 Honduran Liga Nacional
| Season | 2005–06 | 
|---|---|
| Champions | Apertura: Olimpia Clausura: Olimpia  | 
| Relegated | Hispano | 
| UNCAF Interclub Cup | Olimpia Victoria Marathón  | 
| Matches played | 192 | 
| Goals scored | 473 (2.46 per match) | 
| Biggest home win | OLI 6–0 VIC | 
| Biggest away win | HIS 1–5 VIC VID 1–5 VIC  | 
| Highest scoring | VIC 5–4 VID | 
← 2004–05  2006–07 →  
All statistics correct as of 28 May 2006. | |
The 2005–06 season in the Honduran Liga Nacional was the 41st in its history and determined the 47th and 48th champions in the league.