2005–06 Major Indoor Soccer League season
| Season | 2005–06 | 
|---|---|
| Champions | Baltimore Blast  3rd title  | 
| Matches played | 90 | 
| Goals scored | 1,004 (11.16 per match) | 
| Top goalscorer | Giuliano Celenza (38) | 
| Biggest home win | Baltimore 3–12 St. Louis (January 24) | 
| Biggest away win | St. Louis 10–4 Milwaukee (January 13) | 
| Longest winning run | 8 games by Milwaukee (November 6–December 31) | 
| Longest losing run | 11 games by California (November 11–January 1) | 
| Average attendance | 4,737 | 
← 2004–05  2006–07 →   | |
The 2005–06 Major Indoor Soccer League season was the fifth season for the league. The regular season started on November 6, 2005, and ended on April 9, 2006.