2006 Monte Carlo Masters – Singles
| Singles | |
|---|---|
| 2006 Monte Carlo Masters | |
| Champion | Rafael Nadal |
| Runner-up | Roger Federer |
| Score | 6–2, 6–7(2–7), 6–3, 7–6(7–5) |
| Draw | 64 (8 Q / 4 WC / 1 LL ) |
| Seeds | 16 |
Defending champion Rafael Nadal defeated Roger Federer in the final, 6–2, 6–7(2–7), 6–3, 7–6(7–5) to win the singles tennis title at the 2006 Monte Carlo Masters.
This tournament marked the first professional-level match played between Novak Djokovic and Federer, who would go on to play a total of 50 ATP Tour-level matches against each other; Federer won their first-round encounter.