2006 NASDAQ-100 Open – Men's singles
| Men's singles | |
|---|---|
| 2006 NASDAQ-100 Open | |
| Champion | Roger Federer |
| Runner-up | Ivan Ljubičić |
| Score | 7–6(7–5), 7–6(7–4), 7–6(8–6) |
| Draw | 96 (12Q / 5WC) |
| Seeds | 32 |
Defending champion Roger Federer defeated Ivan Ljubičić in the final, 7–6(7–5), 7–6(7–4), 7–6(8–6) to win the men's singles tennis title at the 2006 Miami Open. With the win, Federer achieved his second Sunshine Double (following 2005).