2006 US Open – Wheelchair women's singles
| Wheelchair women's singles | |
|---|---|
| 2006 US Open | |
| Champion | Esther Vergeer |
| Runner-up | Sharon Walraven |
| Score | 6-1, 6-2 |
Defending champion Esther Vergeer defeated Yana Buchina in the final, 6–1, 6–2 to win the women's singles wheelchair tennis title at the 2006 US Open.