2008 Masters Series Hamburg – Singles

Singles
2008 Masters Series Hamburg
Champion Rafael Nadal
Runner-up Roger Federer
Score7–5, 6–7(3–7), 6–3
Draw56 (4WC/7Q/3LL)
Seeds16

Rafael Nadal defeated the defending champion Roger Federer in a rematch of the previous year's final, 7–5, 6–7(3–7), 6–3 to win the singles tennis title at the 2008 Hamburg European Open.

This was the last edition of the tournament played as an ATP Masters Series event, as it was downgraded to an ATP Tour 500 event for the 2009 season.