2008 Sony Ericsson Open – Men's singles

Men's singles
2008 Sony Ericsson Open
Champion Nikolay Davydenko
Runner-up Rafael Nadal
Score6–4, 6–2
Draw96 (12Q / 1LL / 5WC)
Seeds32

Nikolay Davydenko defeated Rafael Nadal in the final, 6–4, 6–2 to win the men's singles tennis title at the 2008 Miami Open. It was his second Masters title.

Novak Djokovic was the defending champion, but lost in the second round to qualifier Kevin Anderson.