2009–10 Cypriot First Division
| Season | 2009–10 | 
|---|---|
| Champions | Omonia 20th title | 
| Relegated | Aris Nea Salamis APEP | 
| Champions League | Omonia | 
| Europa League | APOEL Anorthosis Apollon | 
| Matches played | 218 | 
| Goals scored | 569 (2.61 per match) | 
| Top goalscorer | José Semedo (22 goals) Joeano (22 goals) | 
| Biggest home win | APOEL 5–0 Aris | 
| Biggest away win | Enosis 0-4 Omonia | 
| Highest scoring | Ermis 5-3 Aris | 
| ← 2008–09  2010–11 →  | |
The 2009–10 Cypriot First Division was the 71st season of the Cypriot top-level football league. It started on 29 August 2009. APOEL were the defending champions.