2009–10 UEFA Champions League knockout phase

The knockout phase of the 2009–10 UEFA Champions League began on 16 February and concluded on 22 May 2010 with the final won by Inter Milan against Bayern Munich 2–0 at the Santiago Bernabéu Stadium in Madrid, Spain. The knockout phase involved the sixteen teams who finished in the top two in each of their groups in the group stage.

Times are CET/CEST, as listed by UEFA (local times, if different, are in parentheses).