2012 BNP Paribas Open – Men's singles

Men's singles
2012 BNP Paribas Open
Champion Roger Federer
Runner-up John Isner
Score7–6(9–7), 6–3
Draw96
Seeds32

Roger Federer defeated John Isner in the final, 7–6(9–7), 6–3 to win the men's singles tennis title at the 2012 Indian Wells Masters. It was his record fourth Indian Wells title.

Novak Djokovic was the defending champion, but lost to Isner in the semifinals.