2013 VTR Open – Singles
| Singles | |
|---|---|
| 2013 VTR Open | |
| Champion | Horacio Zeballos |
| Runner-up | Rafael Nadal |
| Score | 6–7(2–7), 7–6(8–6), 6–4 |
| Draw | 28 |
| Seeds | 8 |
Horacio Zeballos defeated Rafael Nadal in the final, 6–7(2–7), 7–6(8–6), 6–4 to win the singles tennis title at the 2013 Chile Open. It was Nadal's first tournament in eight months.
Juan Mónaco was the defending champion, but lost to Guillaume Rufin in the second round.