2015–16 Regional Four Day Competition
| Dates | 6 November 2015 – 18 March 2016 | 
|---|---|
| Administrator(s) | WICB | 
| Cricket format | First-class (four-day) | 
| Tournament format(s) | Double round-robin | 
| Champions | Guyana (8th title) | 
| Participants | 6 | 
| Matches | 30 | 
| Most runs | Leon Johnson (807) | 
| Most wickets | Nikita Miller (65) | 
The 2015–16 Regional Four Day Competition was the 50th edition of the Regional Four Day Competition, the domestic first-class cricket competition for the countries of the West Indies Cricket Board (WICB). The competition ran from 6 November 2015 to 18 March 2016.
Six teams contested the tournament – Barbados, Guyana, Jamaica, the Leeward Islands, Trinidad and Tobago, and the Windward Islands. Guyana were undefeated, winning eight of their ten matches and drawing the other two, and consequently won their eighth title (and second in a row). Jamaica's Nikita Miller was the leading wicket-taker, while Guyana's captain Leon Johnson led the competition in runs.