2016 Regional League Division 2 Eastern Region
| Season | 2016 | 
|---|---|
| Champions | Trat | 
| Matches played | 132 | 
| Goals scored | 360 (2.73 per match) | 
| Top goalscorer | Sarawut Choenchai (15 Goals)  | 
| Biggest home win | Sa Kaeo 10–0 TA Benchamarachuthit (8 May 2016)  | 
| Biggest away win | TA Benchamarachuthit 0–5 Pattaya City (19 March 2016)  | 
| Highest scoring | Sa Kaeo 10–0 TA Benchamarachuthit (8 May 2016)  | 
| Longest winning run | 5 Matches Trat  | 
| Longest unbeaten run | 18 Matches Trat  | 
| Longest losing run | 6 Matches TA Benchamarachuthit  | 
| Highest attendance | 2,206 Cha Choeng Sao 0–1 Sa Kaeo (1 May 2016)  | 
| Lowest attendance | 32 Pattaya City 0–1 Nakhon Nayok (22 May 2016)  | 
← 2015  (T4)2017 →   | |
2016 Regional League Division 2 Eastern Region is the 8th season of the League competition since its establishment in 2009. It is in the third tier of the Thai football league system.