2016 Wimbledon Championships – Women's singles

Defending champion Serena Williams defeated Angelique Kerber in the final, 7–5, 6–3 to win the ladies' singles tennis title at the 2016 Wimbledon Championships. It was her seventh and last Wimbledon singles title and 22nd major singles title overall, equaling Steffi Graf's Open Era record.

This was the first time two women contested multiple major finals in the same season since Amélie Mauresmo and Justine Henin-Hardenne met in the 2006 Australian Open and Wimbledon finals, as Williams and Kerber had contested the 2016 Australian Open final.

In addition to Williams and Kerber, Garbiñe Muguruza, Agnieszka Radwańska and Simona Halep were in contention for the world No. 1 singles ranking. Williams retained the top spot by reaching the fourth round. She also spent her 300th week atop the WTA rankings during the tournament, and won her 300th major match by defeating Annika Beck in the third round.

At 36 years old, Venus Williams was the oldest woman to reach a major semifinal since Martina Navratilova at the 1994 Wimbledon Championships.