2018 Italian Open – Men's singles
| Men's singles | |
|---|---|
| 2018 Italian Open | |
| Champion | Rafael Nadal |
| Runner-up | Alexander Zverev |
| Score | 6–1, 1–6, 6–3 |
| Draw | 56 (7 Q / 4 WC ) |
| Seeds | 16 |
Rafael Nadal defeated defending champion Alexander Zverev in the final, 6–1, 1–6, 6–3 to win the men's singles tennis title at the 2018 Italian Open. It was his record-extending eighth Italian Open title and his record-extending 32nd Masters 1000 title overall. With the win, Nadal also regained the world No. 1 singles ranking.
After failing to defend his runner-up points from the previous year, Novak Djokovic fell outside the top 20 in rankings for the first time since October 2006.