2018 Los Cabos Open – Singles
| Singles | |
|---|---|
| 2018 Los Cabos Open | |
| Champion | Fabio Fognini |
| Runner-up | Juan Martín del Potro |
| Score | 6–4, 6–2 |
| Draw | 28 (4 Q / 3 WC ) |
| Seeds | 8 |
Sam Querrey was the defending champion, but lost in the second round to Egor Gerasimov.
Fabio Fognini won the title, defeating Juan Martín del Potro in the final, 6–4, 6–2.