2018 Western & Southern Open – Men's singles

Men's singles
2018 Western & Southern Open
Champion Novak Djokovic
Runner-up Roger Federer
Score6–4, 6–4
Draw56 (7 Q / 4 WC )
Seeds16

Novak Djokovic defeated Roger Federer in the final, 6–4, 6–4 to win the men's singles tennis title at the 2018 Cincinnati Masters. With this win, he became the first player to complete the career Golden Masters (winning all nine ATP Masters 1000 tournaments over the course of a career) in singles.

Grigor Dimitrov was the defending champion, but lost to Djokovic in the third round.