2018 Wimbledon Championships – Women's singles

Angelique Kerber defeated Serena Williams in the final, 6–3, 6–3 to win the ladies' singles tennis title at the 2018 Wimbledon Championships. It was her third and last major singles title. Kerber was the first German to win the title since Steffi Graf in 1996. Williams was attempting to equal Margaret Court's all-time record of 24 major singles titles, and to become the first mother to win a major singles title since Kim Clijsters won the 2011 Australian Open.

Garbiñe Muguruza was the defending champion, but lost in the second round to Alison Van Uytvanck.

Simona Halep, Caroline Wozniacki and Sloane Stephens were in contention for the world No. 1 singles ranking. Despite losing in the third round, Halep retained the No. 1 ranking after Wozniacki and Stephens lost in the second and first rounds, respectively.

With all of the top ten seeds losing before the quarterfinals, it was the worst overall Wimbledon performance of the top ten women's seeds in the Open Era. This was also the first time in the Open Era that none of the top four women's singles seeds reached the fourth round at Wimbledon.