2019 Mutua Madrid Open – Women's singles

Women's singles
2019 Mutua Madrid Open
Champion Kiki Bertens
Runner-up Simona Halep
Score6–4, 6–4
Draw64 (8 Q / 5 WC )
Seeds16

Kiki Bertens defeated Simona Halep in the final, 6–4, 6–4 to win the women's singles tennis title at the 2019 Madrid Open. She did not lose a set en route to the title, the first to do so since the women's singles event was created in 2009.

Petra Kvitová was the defending champion, but lost to Bertens in the quarterfinals in a rematch of the previous year's final.

Naomi Osaka, Halep and Angelique Kerber were in contention for the world No. 1 singles ranking at the beginning of the tournament. Osaka retained the ranking following Kerber's withdrawal in the second round, and Halep's subsequent defeat in the final.