2019 Winston-Salem Open – Singles
| Singles | |
|---|---|
| 2019 Winston-Salem Open | |
| Champion | Hubert Hurkacz |
| Runner-up | Benoît Paire |
| Score | 6–3, 3–6, 6–3 |
| Draw | 48 (4 Q / 3 WC ) |
| Seeds | 16 |
Daniil Medvedev was the defending champion, but chose not to participate this year.
Hubert Hurkacz won his first ATP Tour title, defeating Benoît Paire in the final, 6–3, 3–6, 6–3. Hurkacz became the first Polish man to win a Tour-level singles title since Wojtek Fibak in 1982.
Lee Duck-hee become the first deaf player to win a main draw match on the ATP Tour when he defeated Henri Laaksonen in the first round.