2020 Australian Open – Women's singles

Sofia Kenin defeated Garbiñe Muguruza in the final, 4–6, 6–2, 6–2 to win the women's singles tennis title at the 2020 Australian Open. It was her first major title. Kenin was the youngest Australian Open finalist since Ana Ivanovic and the youngest champion since Maria Sharapova, both in 2008. This was the first Australian Open final in the Open Era between two players ranked outside the top ten. Kenin entered the top 10 in rankings for the first time by winning the title.

Naomi Osaka was the defending champion, but lost to Coco Gauff in the third round.

This marked the final professional appearance of former world No. 1 and five-time major champion Sharapova, who lost to Donna Vekić in the first round.

The elimination of Angelique Kerber in the fourth round guaranteed a first-time Australian Open champion for the third year in a row. Ons Jabeur became the first Arab woman to reach a major singles quarterfinal, and the first African woman to do so since Amanda Coetzer at the 2001 Australian Open. Anett Kontaveit was the second Estonian to reach a major quarterfinal after Kaia Kanepi. Ashleigh Barty was the first Australian to reach the semifinals since Wendy Turnbull in 1984. Barty's quarterfinal win over Petra Kvitová was her first top ten singles win at a major, having lost her five previous such matches.